AP Biology 12 - Unit 4: Molecular Genetics and Biotechnology
Learning Goal: Are we controlled by our DNA?
- Concept 1: Analyzing the regulation of gene expression and virus cycles (Ch 18, 19 and Inv 7 Part 3)
- Concept 2: Analyzing and utilizing biotechnology tools (Ch 20, AP Inv 8, and AP Inv 9)
- Concept 3: Analyzing genomes and their evolution (Ch 21, AP Inv 3)
- Concept 1: Analyzing the regulation of gene expression and virus cycles (Ch 18, 19 and Inv 7 Part 3)
- Concept 2: Analyzing and utilizing biotechnology tools (Ch 20, AP Inv 8, and AP Inv 9)
- Concept 3: Analyzing genomes and their evolution (Ch 21, AP Inv 3)
Date
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What are we Learning?
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Jan 6
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Introduction
- Current Research: How to grow a retina! - Learning Intentions for Unit - Jigsaw activity for: The Molecular basis of Inheritance (DNA structure/function/replicatio) and From Gene to Protein (protein synthesis) Concept 1: Analyzing the regulation of gene expression and virus cycles (Ch 18, 19 and Inv 7 Part 3) - Discussion with ppt - Complete Mastering Biology online mini-assignment "Gene Expression in Prokaryotes" - Optional Mastering Biology online mini-assignments "Review of DNA Replication" and "Protein Synthesis" |
Jan 8 (x)
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Concept 1: Analyzing the regulation of gene expression and virus cycles (Ch 18, 19 and Inv 7 Part 3)
- Discussion with ppt continued - Trp operon animation - Lac operon animation - Act Out! - Handout: Gene Expression in Bacteria - KEY - Complete Mastering Biology online mini-assignment "Gene Expression in Eukaryotes" |
Jan 12
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Concept 1: Analyzing the regulation of gene expression and virus cycles (Ch 18, 19 and Inv 7 Part 3)
- Remember Histones?: Video - DNA packing - Animation: Regulated Transcription - Challenge: Can you explain this concept to someone else (not taking biology)? Importance, process... - Read p. 356-363 in Campbell, using p. 132 in Holtzclaw as a guide - Handout: Gene Expression in Eukaryotes - KEY - 2009 #4 Free Response |
Jan 14
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Concept 1: Analyzing the regulation of gene expression and virus cycles (Ch 18, 19 and Inv 7 Part 3)
- Act Out! - Discuss Gene Expression in Eukaryotes - Read/skim p. 366-378 in Campbell and p. 132-134 in Holtzclaw, focusing on embryonic development and cancer. - Answer Questions #1, 3, 5, 6, 7, 8, 11, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 30, 33 from p. 143-147 in Holtzclaw. |
Jan 23
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Concept 2: Analyzing and utilizing biotechnology tools (Ch 20, AP Inv 8, and AP Inv 9)
Bring a Device Virtual Lab AP Investigation 9: Biotechnology - Restriction Enzyme Analysis of DNA - Activity: Virtual PCR Lab - Activity: Virtual Electrophoresis Lab - Activity: LabBench Gel Electrophoresis - Investigation from Campbell: How can gel electrophoresis be used to Analyze DNA? Handout and KEY - Complete Mastering Biology online mini-assignment "Biotechnology" |
Jan 27
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Concept 2: Analyzing and utilizing biotechnology tools (Ch 20, AP Inv 8, and AP Inv 9)
- Discuss with ppt and animations - Bacterial Transformation: Prep for AP Investigation 8 |
Jan 29
Bl 1-1 |
Concept 2: Analyzing and utilizing biotechnology tools (Ch 20 and AP Inv 8)
- Lab Inv 8 - Molecular Genetics (Transformation - Let's make bacteria glow!): Day 1 - Set Up Transformation |
Jan 30 LUNCH
(1:00) |
Concept 2: Analyzing and utilizing biotechnology tools (Ch 20 and AP Inv 8)
- Lab Inv 8 - Molecular Genetics (Transformation - Let's make bacteria glow!) Day 2 - Results ![]() Thank you to Gagarin for the photo :)
Successfully transformed E coli from 2012 Awesome info about GFP (green fluorescent protein) - Click here, here, here, and here Other transgenic organisms using GFP - Click here and here Medical Research application - Click here and here |
Feb 2
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Concept 2: Analyzing and utilizing biotechnology tools (Ch 20, AP Inv 8, and AP Inv 9)
- Discuss Transformation Results. Ensure you are through with your explanations. - Short Free Response Flashback to Biochem/Cells Unit - Long Free Response Surprise! 2007#4 - Complete Mastering Biology online mini-assignment "Genomes and their Evolution" |
Feb 4
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Concept 3: Analyzing genomes and their evolution (Ch 21, AP Inv 3): retrotransposons, evo-devo, homeoboxes
Bring a Device - Respect to Sanger - AP Investigation 3: Comparing DNA Sequences to understand Evolutionary Relationships with BLAST - Read: Making an Embryo - Read: DNA double take - Watch: RNA Interference - Read: Transposons |
Feb 10
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AP Lab Investigation 8 DUE
Checkpoint #2 - Concept 2 and 3 - Article Link: DNA's New Alphabet - Science Article: "Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome": Read (skim) and highlight all terminology you recognize! Pay special attention to the introduction, the figures, and the discussion. For next class, be ready to discuss: What is the relevance/significance of this research article? |
Feb 12
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Review
- Free Response Examples (2014 #2a, 5, 8, 2013 #5, 2012 #3, 2009 #4, 2009B #1, 2007 #4, 2002 #1) - All Questions in Holtzclaw for Topic 5 (Molecular Genetics), Inv 8 (Bacterial Transformation), Inv 9 (Rest Enz Analysis of DNA) - AP Test Format: Read pg. 10-24 in Holtzclaw - Our Unit Test: 75 min: (40 min: 28 MC, 2 Grid-in; 3 min: Free Response Reading; 32 min: 1 long free, 2 short free) |
Feb 16
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Unit Test
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